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Tomoyuki Koike Selected Research

Achlorhydria (Hypochlorhydria)

7/2015Endoscopic findings for predicting gastric acid secretion status.
1/2014Cutoff serum pepsinogen values for predicting gastric acid secretion status.
2/2013Gastric hypochlorhydria is associated with an exacerbation of dyspeptic symptoms in female patients.
11/2010Deficient aldehyde dehydrogenase 2 is associated with increased risk for esophageal squamous cell carcinoma in the presence of gastric hypochlorhydria.

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Tomoyuki Koike Research Topics

Disease

23Infections
10/2017 - 11/2003
13Gastroesophageal Reflux (GERD)
01/2022 - 03/2004
12Neoplasms (Cancer)
10/2022 - 01/2012
12Stomach Neoplasms (Stomach Cancer)
01/2022 - 11/2003
10Peptic Esophagitis (Reflux Esophagitis)
01/2022 - 03/2004
8Hemorrhage
04/2022 - 01/2015
7Peptic Ulcer (Peptic Ulcers)
11/2018 - 04/2013
7Atrophy
07/2015 - 11/2006
6Non-Erosive Reflux Disease
01/2022 - 11/2011
5Barrett Esophagus (Barrett's Esophagus)
01/2022 - 08/2005
5Ulcer
11/2018 - 04/2013
5Inflammation (Inflammations)
04/2018 - 01/2009
4Lymphatic Metastasis
01/2022 - 09/2019
4Carcinogenesis
11/2020 - 01/2012
4Esophageal Squamous Cell Carcinoma
09/2020 - 11/2010
4Marginal Zone B-Cell Lymphoma (MALT Lymphoma)
07/2015 - 01/2008
4Achlorhydria (Hypochlorhydria)
07/2015 - 11/2010
3Esophagitis
01/2018 - 01/2009
3Metaplasia
03/2016 - 01/2009
3Pathologic Constriction (Stenosis)
06/2015 - 10/2012
2Deglutition Disorders (Dysphagia)
10/2022 - 10/2012
2Carcinoma (Carcinomatosis)
12/2020 - 05/2013
2Wounds and Injuries (Trauma)
06/2020 - 01/2013
2Stomach Ulcer (Gastric Ulcer)
05/2015 - 01/2011
2Varicose Veins (Varicose Vein)
11/2014 - 08/2012
2Gastritis
09/2013 - 02/2009
2Abdominal Pain (Pain, Abdominal)
01/2013 - 06/2012
2Lymphoma (Lymphomas)
11/2012 - 01/2008
2Atrophic Gastritis
11/2006 - 03/2004
1Hemangioma (Angioma)
08/2022
1Blepharoptosis (Ptosis, Eyelid)
09/2021
1Duodenitis
08/2021
1Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
08/2021
1Parkinson Disease (Parkinson's Disease)
06/2021
1Amyloid Plaque
05/2021
1Polyps
02/2021
1Adenocarcinoma
02/2021
1Constipation
02/2021
1Chronic Renal Insufficiency
01/2021
1Colic (Abdominal Cramps)
12/2020
1Eructation (Eructations)
11/2020
1COVID-19
09/2020
1Comminuted Fractures
06/2020
1Fracture Dislocation
06/2020
1Refractory Anemia
03/2020
1Heart Failure
03/2020
1Aortic Valve Stenosis (Aortic Stenosis)
03/2020

Drug/Important Bio-Agent (IBA)

18AcidsIBA
10/2022 - 03/2004
14Proton Pump InhibitorsIBA
10/2022 - 01/2011
7GastrinsIBA
05/2015 - 04/2004
6Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2022 - 03/2004
51- (5- (2- fluorophenyl)- 1- (pyridin- 3- ylsulfonyl)- 1H- pyrrol- 3- yl)- N- methylmethanamineIBA
04/2022 - 01/2021
5Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
07/2016 - 01/2013
5Pharmaceutical PreparationsIBA
05/2015 - 04/2008
5Pepsinogen A (Pepsinogen)IBA
01/2014 - 10/2005
3PotassiumIBA
10/2022 - 01/2021
3Phenobarbital (Luminal)FDA Link
01/2022 - 01/2009
3Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
01/2021 - 05/2011
3Indicators and Reagents (Reagents)IBA
01/2018 - 01/2009
3AntralIBA
07/2016 - 01/2011
3Immunoglobulin G (IgG)IBA
12/2012 - 07/2004
3UreaseIBA
11/2012 - 07/2004
2Fibrinolytic Agents (Antithrombotic Agents)IBA
01/2022 - 01/2021
2Dihydrotachysterol (AT 10)IBA
02/2021 - 03/2020
2Estrogens (Estrogen)FDA Link
01/2018 - 04/2016
2Biomarkers (Surrogate Marker)IBA
01/2017 - 02/2009
2Proteins (Proteins, Gene)FDA Link
07/2015 - 08/2009
2AcetaldehydeIBA
01/2015 - 11/2010
2Congo RedIBA
01/2012 - 01/2009
2Rabeprazole (Aciphex)FDA Link
11/2011 - 09/2006
2AntibodiesIBA
01/2009 - 07/2004
2Ascorbic Acid (Vitamin C)FDA LinkGeneric
01/2009 - 11/2003
2Cytochrome P-450 CYP2C19IBA
02/2007 - 09/2006
1SecretagoguesIBA
10/2022
1Protein Kinases (Protein Kinase)IBA
01/2022
1Heparin (Liquaemin)FDA LinkGeneric
01/2022
1Polytetrafluoroethylene (Teflon)FDA Link
09/2021
1SuspensionsIBA
09/2021
1Carbidopa (Lodosyn)FDA LinkGeneric
06/2021
1Levodopa (L Dopa)FDA LinkGeneric
06/2021
1Amyloid (Amyloid Fibrils)IBA
05/2021
1Purinergic P2Y Receptor AntagonistsIBA
01/2021
1AnticoagulantsIBA
01/2021
1Cilostazol (Pletal)FDA LinkGeneric
01/2021
1Warfarin (Coumadin)FDA LinkGeneric
01/2021
1SOXB1 Transcription FactorsIBA
11/2020
1AerosolsIBA
09/2020

Therapy/Procedure

15Therapeutics
03/2022 - 08/2005
3Gastrectomy
01/2022 - 08/2019
2Chemoradiotherapy
09/2020 - 03/2015
2Sclerotherapy
11/2014 - 08/2012
1Dye Lasers
08/2022
1Heart-Assist Devices
08/2021
1Renal Dialysis (Hemodialysis)
02/2021
1Salvage Therapy
01/2021
1Pancreaticoduodenectomy
12/2020
1Palliative Care (Palliative Therapy)
12/2020
1Esophagectomy
09/2020
1Arthroplasty
06/2020
1Transcatheter Aortic Valve Replacement
03/2020